Primary Leiomyosarcoma of the Breast with Unusual Metastasis

Primary leiomyosarcomas of the breast are extremely rare tumors, with unpredictable biological behavior. The main treatment consists of wide resection or mastectomy. Local recurrence is late; the distant metastasis spreads via the hematogenous route to lungs and liver; however, bone metastasis is rarely reported. Here, we present a case of primary leiomyosarcoma of the breast, diagnosed in the postmenopausal female. She underwent a wide resection with free margins. The patient rapidly, presented an unusual aggressive behavior of leiomyosarcoma, with a local recurrence in axillary lymph node and an exceptional distant metastasis in bones.