Anaphylaxis: A Life-Threatening Hypersensitivity Reaction

Anaphylaxis is an acute, life-threatening systemic hypersensitivity reaction, primarily mediated by immunoglobulin E. Food allergy is the most common trigger, followed by medications. Patients with anaphylaxis typically present with cutaneous or mucosal symptoms, often accompanied by respiratory and gastrointestinal manifestations. Epinephrine remains the first-line treatment for anaphylaxis. It is crucial to educate patients and caregivers on recognizing anaphylactic symptoms and the proper use of epinephrine autoinjectors.