ASSOCIATION OF HbA1c, FASTING GLUCOSE LEVELS AND LIPID PARAMETERS WITH ANTHROPOMETRIC INDICES IN A GROUP OF DIABETICS AND NON-DIABETIC INDIVIDUAL

INTRODUCTION: Because of the usefulness of anthropometric measurements and indices, they are frequently recommended for prediction of diabetes in clinical practice. The aim of this study is to determine the relationship between HbA1c and fasting plasma glucose (FPG) and lipid parameters of diabetics and non-diabetics and 7 different indices, such as, waist circumference (WC), waist-to-hip ratio (WtHR), body mass index (BMI), Broca-Katsura index, Rohrer index, a body shape index (ABSI), and body roundness index (BRI).
METHODS: A total of 505 individuals were included in the study (type 2 DM, n=65; type 1 DM, n=265, and 171 controls). Anthropometric measurements were evaluated (weight, height and waist circumference) and from these measurements BMI, Broca-Katsura Index, Rohrer Index, ABSI and BRI were calculated. HbA1c, FPG, LDL-cholesterol, triglyceride and HDL-cholesterol levels were also measured. Data were analysed with SPSS 21.0 statistics program.
RESULTS: HbA1c levels and BMIs were significantly high in diabetic patients. None of the indices were significantly correlated with HbA1c, FPG levels, LDL-cholesterol and triglyceride levels in diabetic patients; but body weight, body mass, BMI, WC and BrocaKatsura index were positively correlated with HbA1c levels in controls. On the other hand, FPG levels of controls were positively correlated with body weight, BMI and Broca-Katsura index.
DISCUSSION AND CONCLUSION: Although much of the anthropometric measurements and indices correlated with the levels of HbA1c, FPG and LDLcholesterol, HDL-cholesterol and triglycerides in control group; none of the indices were correlated with HbA1c levels, FPG, LDLcholesterol and triglyceride in type 1 and type 2 diabetics. Anthropometric indices, especially recent ones, had limited capacity and usefulness for monitoring of diabetes and dyslipidemia in diabetic patients.