INTRODUCTION: Osteoporosis is one of the health issues caused by smoking. Osteoporosis is the most commonly seen bone disease and becoming a major public health issue due to rise of death age.Studies on detection of smoking related osteoporosis in males are limited in our country. Therefore we intended to assess the effects smoking on bone mineral density in middle age male patients alongside with related factors.
METHODS: Our study is a case control type analytical research. We included 144 male 30-60 aged smoker patient and 100 male never smoked. BMD of the patients' lumbar vertebrae (L1-3 and L2-4) and proximal femur (femur total, femur trochanter and wards triangle) regions of the individuals were measured anteroposteriorly by using dual energy x-ray absorptiometer (DXA) method. Serum Ca, P, ALP, PTH and total vitamin D levels of the samples were studied.
RESULTS: L1-L4 lumbar spine bone mineral density mean, femoral neck bone mineral density mean, femoral trochanter bone mineral density mean and total femoral bone mineral density mean were significantly lower in case group than control group, according to DXA measurements (p=0,017 p=0,047 p=0,005 p=0,009). There was slightly strong correlation and negative statistically significant difference between femoral trochanter BMD and both cigarette consumption (per-day) and packets.year (r: -0,153, p=0,017 r: -0,142, p=0,027).Mean serum calcium levels were significantly higher in case group than control group (p=0,018).
DISCUSSION AND CONCLUSION: We can conclude that bone mineral density decreasing effects of smoking.